The Cyprus Marine and Maritime Institute, is a newly established independent, international, scientific and business Centre of Excellence for Marine and Maritime Research, Technological Development and Innovation that aims to be driven by the needs of the Industry and Society in addressing the major Challenges that the Marine and Maritime sectors face. To achieve this, the CMMI will perform world-class, business-relevant, and applied multidisciplinary RTDI activities as well as training, education and entrepreneurship support activities. The CMMI was the outcome of the MaRITeC-X project which was funded under the “H2020 Programme, Spreading Excellence and Widening Participation Call”. As a result of this project, the CMMI was awarded €30 million funding from the EU Commission and the Cyprus Government, while more than €25 million are to be provided by partners and industry and academia stakeholders mainly as in-kind contributions in a 7-year period. After that period, the CMMI is expected to be a self-sustaining entity. In addition, the CMMI is based in Larnaca, Cyprus, but will have regional and global reach. In particular, the CMMI will promote partnerships, globally, among top academic and research institutions and businesses, helping to address the needs of businesses, countries, and regions in blue economy activities. All in all, the CMMI aims to become the partner of choice for all blue economy development activities at the local, regional, European, and global levels.