Nanotechnology / Projects

Second Programme of Community action in the Field of Health 2008-2013
Safety evaluation of manufactured nanomaterials by characterisation of their potential genotoxic hazard [NANOGENOTOX]
Human exposure to manufactured nanomaterials (MNs) used in consumer products may occur during several phases of their life cycle. The lack of scientific knowledge makes regulation difficult.

The aim ...
Human exposure to manufactured nanomaterials (MNs) used in consumer products may occur during several phases of their life cycle. The lack of scientific knowledge makes regulation difficult.

The aim of the Joint Action is to establish a robust methodology to assess the potential genotoxicity of MNs and to generate data on the genotoxic effect of certain reference materials (www.nanogenotox.eu).

The JA specific objectives are:
To obtain detailed physicochemical properties for each selected MN
To determine the influence of exposure media on MNs dispersability and to identify the optimum preparation protocols for the specific MNs
To generate in vitro genotoxicity data on MNs
To perform a round robin test on in vitro genotoxicity testing of MNs
To determine relevant doses and sampling time for biodistribution and in vivo genotoxicity studies, and to identify MN accumulation in organs for in vivo genotoxicity tests
To generate data from in vivo genotoxicity selected tests, and to assess the correlation between in vivo and in vitro results taking into account the kinetic results
Start date: 01/03/2010 - End date: 01/03/2013

Call: Improve Citizen''S Health Security (Hs-2009)
Topic: Nanotechnology
3rd Health Programme (2014-2020)
Promoting Implementation of Recommendations on Policy, Information and Data for Rare Diseases [RD-ACTION]
Rare diseases (RD) have been identified as one of the paradigmatic fields in which actions conducted at the European level constitute the adequate response to their specific problems: poor recognition...
Rare diseases (RD) have been identified as one of the paradigmatic fields in which actions conducted at the European level constitute the adequate response to their specific problems: poor recognition leading to diagnostic delay and inappropriate management including adapted social services, poor health outcomes, social burden, limited knowledge on natural history and pathophysiology leading to an insufficient development of new therapies. The low prevalence and the specificity of RD make that a global, multi-stakeholder approach, intended to gather specific expertise and to build shared strategies is necessary to address these issues.
The general objectives of RD-Action are to:
▪ Support the further development and sustainability of the Orphanet database, the biggest global repository of information on RD
▪ Contribute to solutions to ensure an appropriate codification of RD in health information systems
▪ Continue implementation of the priorities identified in Council Recommendation 2009/C151/02 and the Commission Communication (COM 2008 679) on RD, with a view to ensuring the sustainability of the recommended priority actions and to support the work of the Commission Expert Group on Rare Diseases (CEGRD).
This JA will expand and consolidate the achievements of the former JAs on RD supported by the European Commission: the Orphanet JA and the EUCERD JA. More precisely, this proposal has the ambition to help member states to implement the recommended measures adopted or to be adopted by the CEGRD and to produce the data necessary for countries to do so. Interactions between the production of data at the Orphanet database level and the implementation of policy priorities including codification will be strengthened during this JA.RD-Action large geographical coverage is key to success as it will promote the transfer of European recommendations into national policies and the collection of information and concerns from MS to the CEGRD, thus to the European Commission.

Start date: 01/06/2015 - End date: 31/07/2018

Call: Grants for actions co-financed with Member State authorities 2014 (Joint Actions)
Topic: Nanotechnology